Materials and Methods Plant material Justicia carnea leaves used in this study were collected from Ozalla Isuofia in Anambra State and identified by Mr. Ozioko PDF Evaluation of Anti-inflammatory and Analgesic Properties of Justicia I also conduct research on molecular basis of human diseases, linking the pharmacological properties of certain natural products and their mechanisms of actions to the treatment of such diseases. Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. DOI: https://doi.org/10.1089/ars.2007.1901. Prof. F.O. The Hematological system and antioxidant status of rats following 14days of sub-acute exposure tolerated the ethanol extract of J. carnea leaf. I do hope that after reading through this article, you would plan to start cultivating this amazing plant specie in your garden. J Ethnopharmacol. It also grows in some Caribbean islands, including Trinidad and Tobago. Cookies, This site is protected by reCAPTCHA and the Google, Justicia scheidweileri (Purple Shrimp Plant), Justicia americana (American Water-Willow), Want Garden Inspiration? 50mg/kg-1200mg/kg treatment relative to control treatment showed varied degree of renal injury that is dose dependent. Acute toxicity was determined in two phases using Lorke method. Excitedly, scientific studies have supported the traditional claims. Therefore,it is imperative to investigate the effects of the plant on the essential biochemical indices in diabetic rats so as to establish its safety. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Biomed Environ Mass Spectrom 1988;15(8):413-417. Having discussed the nutritional benefits of ewe eje, i shall now take you through the various health benefits of justicia carnea leaves, and roots. It has been shown also that other specie of justicia improve central nervous system functions and health and protect it from toxic damages. J Ethnopharmacol. The plant possess several bioactive compounds like polyphenols, which act as antioxidants or anti-inflammatory compounds. It is nicknamed the Blood leaf, Blood of Jesus, and Jehovah Witness leaf in Nigeria, and is a widely used leaf across states in Nigeria. Oso BJ, Oyewo EB and Oladiji AT. View abstract. 2. Anal Biochem. 2010;4(8):6804 https://doi.org/10.5897/JMPR09.487. Phytochemical profile, antioxidant, -amylase inhibition, binding Authors KOK and ESA performed the statistical analysis and managed the analyses of study. There may be some problems if the air is too dry in winter. This plant is somewhat drought-tolerant once established but looks best with regular watering during periods of extended dry weather. Correspondence to Meth Enzymol. Some people would rather chew the leaves, while others add to meals or brew into a tea (in combination with other plants). Research reports it isn't capable of . Effect of methanol leaf extract of Justicia carnea on serum albumin (ALB) and total protein (TP) concentration CCl 4 intoxicated rats. Effect of Tectona grandis on phenylhydrazine induced anemia in rats. Oral acute toxicity study on J. carnea ethanol extract (JCEE) was carried out according to Lorke [15] method using the total of twelve (12) albino rats in two phases. It may be, judging from the antidepressant activity of other plant of justicia species whose activity have been studied, proper to state that justicia carnea may possess antidepressant properties. There are several nutritional benefits of justicia carnea leaves. ESA conceived and designed the study. According to acute toxicity grading standards, LD50 of substances greater than 5000mg/kg is practically considered non-toxic [22, 23]. The antioxidants in Justicia carnea helps protect the liver and the heart from toxic agents and free radicals. California Privacy Statement, It also can be used in combination with other vegetables such as the Efinrin (scent leaves), ugwu etc. Side Effects, Uses and Health benefit of Ewe eje (Justicia carnea leaf) 2015;6(7):265270. It is believed by local consumers in Ghana to possess anti-anaemic effects that boost blood levels in pregnant women, anaemic patients and also . WBC reduced in rats treated with doses of J. carnea with significant decrease (p<0.05) in rats that received 50, 100 and 1200mg/kg body weight. Influence of ethanolic extracts of dried fruit of Xylopia aethiopica (Dunal) A. Joseph, H., Gleye, J., Moulis, C., Mensah, L. J., Roussakis, C., and Gratas, C. Justicidin B, a cytotoxic principle from Justicia pectoralis. Biochemistry Unit, Department of Chemical Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Nigeria, Emmanuel Sina Akintimehin,Kayode Olayele Karigidi,Tope Samuel Omogunwa&Foluso Olutope Adetuyi, You can also search for this author in Regular intake can reduce your risk of liver diseases like liver cirrhosis, hepatitis and liver inflammation. This claim by traditional healers with regard to the efficacy of justicia carnea in the treatment diabetes have been researched on and it was found to be true. McCune LM, Johns T. Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the indigenous peoples of the north American boreal forest. Bottom Line. Except the group that received 1200mg/kg JCEE which showed significant (p<0.05) elevation of SOD and MDA in the liver, other doses (<1200mg/kg) demonstrated no significant difference compared to the control. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. Ogwu obara can act as a blood tonic for women during menstruation. Part of Also observed is a distortion in the walls of the blood vessels (red arrow), pyknotic hepatocytes and signs of inflammation (red arrow), Photomicrographs of kidney sections stained with Haematoxylin and Eosin (Mag. Relative to control, lymphocyte and granulocyte exhibited no significant difference in all doses while MID was elevated in treated groups with significant increase in rats administered with 500 and 800mg/kg body weight. In various parts of Africa, several species of Justicia are used in traditional medicine for the treatment of anemia, inflammation, fever, diarrhea, liver diseases and arthritis respiratory and gastrointestinal disorder [8, 9]. The kidney of rats treated with doses of J. carnea ethanol extract revealed dose dependent degree of renal injury (Fig. In a study conducted by Onyeabor and colleagues, the leaf extract of jusiticia carnea reverses the anemic effect of phenylhydrazine on the pack cell volume, red blood cell, and hemoglobin concentrations. Joseph, H., Gleye, J., Moulis, C., Fouraste, I., and Stanislas, E. O-Methoxylated C-glycosylflavones from Justicia pectoralis. It is very rich in iron, a major component is RBC hemoglobin. if you add justicia carnea leaves in avocado seed tea, you may just get yourself the best remedy for cardiovascular diseases. International Journal of Biochemistry Research & Review. hindawi publishing corporation evidence-based complementary and alternative medicine. The aqueous leaf extract of ewe eje has demonstrated hypoglycaemic and antidiabetic properties; and thus, can be said to assist with blood sugar levels reduction. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. The changing faces of glutathione, a cellular protagonist. Springer Nature. In this report, MCV, MCH and MCHC in treated group were not altered compared to the control. The Pharmacobiochemical Effects of Ethanol Extract of Justicia secunda Ewe eje is safe and healthy for consumption. Summarily, experimental group shows some degenerative changes that can be termed as necrosis, some mild fibrosis and hemorrhage characterized by the presences of infiltrated red hemorrhagic and inflammatory cells. 2008; 10:2. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. Justicia carnea (belonging to Acanthaceae family) is a flowering plant consisting ~600 species that are widely distributed in the tropics and subtropics [7]. Despite the therapeutic importance of medicinal plants, toxic substances have been shown to be present in large numbers of plants investigated [3]. The blood stimulating effects could be due to the presence of dietary bioactive constituents that stimulate activities of haematopoietic cells and stabilization of blood in circulation [21]. Differences between means were considered to be significant at (p<0.05) using LSD (Least Square Difference) post hoc test. Control treatment showed normal central venules without congestion, the morphology of the hepatocytes appear normal, the sinusoids appear normal with no observable form of infiltration and no observable pathological lesion seen. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. The Health benefit of Ewe eje (Justicia carnea leaf) are highlighted in this article. Lipid peroxidation was determined by measuring the formation of thiobarbituric acid reactive substances (TBARS) according to the method described by Buege and Aust [20]. The shrubby habit of the plant is well-suited for both containers and outside planting. In the study conducted by Onyeabor and his colleagues, it was shown that the leaf extract not only reverses anemic condition, but also lowered the lipid profile of the experimental rats. Prevent this by spraying the leaves with water. They range in colors such as red, orange, mauve, magenta, apricot, and pink. J Afr Ass Physiol Sci. You can add milk or honey for taste before drinking. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. At the end of the 14th day of administration, the rats were allowed to fast overnight and sacrificed the following morning by anesthetizing each rat in a closed chamber containing drops of chloroform. Justicia Betonica Herb Uses, Benefits, Cures, Side Effects, Nutrients Compared to the control, total protein in liver and kidney were statistically not altered except rats that were administered with 1200mg/kg JCEE that showed significant (p<0.05) decrease in the liver.
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